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UCLA Clinical and Translational Science Institute

Navigating the UCLA CTSI

May 10, 2013

Marisa Briones, PhD Research Facilitator Office of Investigator Services ctsi.ucla.edu

NCATS Clinical and Translational Science Award

UCLA CTSI is part of a national consortium of 60 medical research institutions

? Accelerate the process of translating laboratory discoveries into treatments for patients

? Engage communities in clinical research efforts

? Train a new generation of clinical and translational researchers

Accelerating Discoveries Towards Better Health

Purpose of the National CTSA Program

Providing an infrastructure for clinical and translational research

OLD

NEW

Inpatient GCRC

Outpatient & community based research

Individual investigators

Transdisciplinary team science

Traditional training

Individual academic medical centers

Training in clinical and translational team science

Regional and national consortia

linked for collaboration

3

UCLA Clinical and Translational Science Institute

? Public research university with leading medical, dental, public health, nursing, engineering, business and life sciences

? Cedars-Sinai Medical Center is the largest nonprofit hospital in the western United States

? An academic institution serving the under-resourced Watts-Willowbrook communities of South Los Angeles

? Public teaching and research hospital; its catchment area of 3 million residents includes 550,000 below the poverty level

UCLA Clinical and Translational Science Institute

Ethnic Composition LA 2007

White

Hispanic

Asian

Pacific Islander Black

American Indian MultiRace

Adapted from SUSTAIN presentation, Vickrey, 2011

? > 10 million people

? no ethnic majority

? 107 languages

? The county's population is larger than that of 42 states

? 30% are under age 18 and 20% are below the federal poverty line

? 25% lack health insurance ? A 15-year life expectancy gap

separates our healthiest and sickest populations

Mission: Create a borderless clinical and translational research institute that brings UCLA innovations and resources to bear on the greatest health needs in Los Angeles.

UCLA CTSI Program Areas

Consultation, support services and resources available:

Biomedical Informatics Program

? Resources and infrastructure for acquisition, storage and analysis of data

Biostatistics and Computational Biology

? Project design, biostatistics, clinical data management and computational biology

Center for Translational Technologies

? Access to more than 100 biomedical cores across CTSI campuses

Clinical and Community Research Resources

? Supports clinical research at the Clinical and Translational Research Centers

Research Education, Training, and Career Development

? Conducts and coordinates clinical and translational science education

Community Engagement and Research Program

? Links investigators and local communities, consultation program

Evaluation Program

? Health services research, cost analysis, evaluations, surveys

Pilot and Collaborative Translational and Clinical Studies Program

? Supports multidisciplinary pilot studies and the development of novel methodologies and technologies

Regulatory Knowledge and Support, Industry Relations, and Research Ethics

? Regulatory compliance, IRB, data safety monitoring, post-approval oversight

Committee on Maternal, Child and Adolescent Health